Absolute hand determination of glycofibrils from natural sources in cryo-EM
Qi Zhang, Li Qin, Tongtong Wang, Zhangqiang Li, Yilin Zhang, Sheng Chen, Qijun Ge, Jialing Wen, Nieng Yan, Jiawei Wang, Mingxu Hu
This study introduces Ahaha, a method for determining absolute hand of glycofibrils in cryo-EM, enabling atomic model building from natural sources.
Proceedings of the National Academy of Sciences · Feb 25, 2026Peer-reviewedBiophysics