Author

Zhangqiang Li

Center for Life SciencesORCID 0000-0002-3296-2293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Nieng YaniD· 3 shared Tongtong WangiD· 3 shared Mingxu HuiD· 2 shared Yitong SuniD· 2 shared Chuangye YaniD· 1 shared Jialing Wen· 1 shared Jiawei WangiD· 1 shared Kui XuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

Nieng YanORCID

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3 papers

Recent·Most cited

CryoSeek identification of glycofibrils with diverse compositions and structural assemblies

Zhangqiang Li, Tongtong Wang, Yitong Sun, Kui Xu, Wenze Huang, Qiangfeng Cliff Zhang, Chuangye Yan, Mingxu Hu, Nieng Yan

The paper characterizes five new glycofibrils isolated from Tsinghua Lotus Pond using cryo-EM and AI, revealing structural diversity in their central protein components and glycans.

Cell chemical biology · Apr 20, 2026Peer-reviewedBiophysics

Absolute hand determination of glycofibrils from natural sources in cryo-EM

Qi Zhang, Li Qin, Tongtong Wang, Zhangqiang Li, Yilin Zhang, Sheng Chen, Qijun Ge, Jialing Wen, Nieng Yan, Jiawei Wang, Mingxu Hu

This study introduces Ahaha, a method for determining absolute hand of glycofibrils in cryo-EM, enabling atomic model building from natural sources.

Proceedings of the National Academy of Sciences · Feb 25, 2026Peer-reviewedBiophysics

The 8-nm spaghetti: well-structured glycans coating linear tetrapeptide repeats discovered from freshwater with CryoSeek

Tongtong Wang, Yitong Sun, Zhangqiang Li, Nieng Yan

The paper discovers a new glycofibril structure using CryoSeek, revealing its 8-nm diameter and unique glycan-coated tetrapeptide repeats.

bioRxiv · Dec 15, 2024 · PreprintBiophysics