Pan-cancer nucleosome landscapes reveal tumor heterogeneity and inform cell-free DNA-based detection
Shen Yang, Jialuo Ye, Jinqi Yuan, Xiaoqian Huang, Yue Yin, zhaoying Liu, Wei Li, Yumei Li
The paper characterizes nucleosome organization across 23 cancer types using ATAC-seq and shows its utility for cancer classification and detection using cell-free DNA.
bioRxiv · Oct 18, 2026 · PreprintBioinformatics