Widely used CaMKII regulatory segment mutations cause tight actinin binding and dendritic spine enlargement in unstimulated neurons
Ashton J. Curtis, Jian Zhu, Dorota Studniarczyk, Timothy W. Church, Mark Farrant, Matthew G. Gold
This study shows that CaMKII T305A/T306A mutations cause tight actinin binding and dendritic spine enlargement in unstimulated neurons, suggesting a structural role for CaMKII in LTP.
Journal of Neuroscience · Oct 23, 2025Peer-reviewedNeuroscience