Author

Jian-Kang Zhu

Macau University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert MironenkoviD· 1 shared Baichuan DengiD· 1 shared Fengge Xu· 1 shared Jiajun LeiiD· 1 shared Jianhong Pan· 1 shared Meiling Lai· 1 shared Ming Li· 1 shared Minglei SongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

Albert MironenkovORCID

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2 papers

Recent·Most cited

PhysiologyBiogerontologyPeer-reviewedOct 1, 2026

Sex-stratified immune patterns across the canine lifespan and short-term responses to geroprotective interventions

Meiling Lai, Fengge Xu, Yingxia Xu…·Yuxuan Lu

This study examines age-related immune changes and short-term responses to geroprotective interventions in dogs, finding sex-stratified cytokine patterns and varied intervention effects.

DOI 10.1007/s10522-026-10518-w

bulk RNA-seqstatistical model

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintSep 28, 2026

Reassessing the contribution of the histone H3 tail to KRAB-DNMT3L-mediated epigenetic silencing

Minglei Song, Jiajun Lei, Jian-Kang Zhu

The paper evaluates the role of the histone H3 tail in KRAB-DNMT3L-dCas9-mediated gene silencing and finds it does not provide a general functional advantage.

DOI 10.64898/2026.09.24.753995

humanCRISPR screen

𝕏 PostBluesky