Synthetic BiologybioRxivPreprint
Reassessing the contribution of the histone H3 tail to KRAB-DNMT3L-mediated epigenetic silencing
Minglei Song, Jiajun Lei, Jian-Kang Zhu
The paper evaluates the role of the histone H3 tail in KRAB-DNMT3L-dCas9-mediated gene silencing and finds it does not provide a general functional advantage.
DOI 10.64898/2026.09.24.753995