Extracellular loops of the β-barrel domain catalyze rapid folding for function of self-associating autotransporters
Xiaojun Yuan, Matthew D. Johnson, Jiansi Long, Jing Zhang, Alvin W. H. Lo, Jason J. Paxman, Minh‐Duy Phan, Begoña Heras, Mark A. Schembri, Gerard H. M. Huysmans, Ian R. Henderson, Matthew Thomas Doyle, Denisse L. Leyton
This study shows that extracellular loops of the β-barrel domain in Ag43 are essential for passenger domain folding and bacterial aggregation.
bioRxiv · Apr 8, 2025 · PreprintBiochemistry