Author

Jiawei Yan

Guangzhou Laboratory

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Deqi CheniD· 1 shared Feng ZhangiD· 1 shared Haopeng LiniD· 1 shared Huisheng LiuiD· 1 shared Jiaxiang YiniD· 1 shared Kuo Jiang· 1 shared Lihua CheniD· 1 shared Peng XueiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Deqi ChenORCID

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1 paper

Recent·Most cited

Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism

Haopeng Lin, Xin Liu, Feng Zhang, Deqi Chen, Xiaoxiao Xie, Qifei Dong, Jiawei Yan, Jiaxiang Yin, Zirong Bi, Zhihua Dou, Yingling Jiang, Kuo Jiang, Tongran Zhang, Peng Xue, Wei Peng, , Huisheng Liu

This study identifies PKM1-regulated PEP metabolism as a key factor in improving functional maturation of human stem-cell derived β cells by enhancing calcium response and insulin secretion.

Nature Communications · Dec 21, 2025Peer-reviewedCell Biology