Jie J. Zheng

This study quantifies single-cell contractility in human trabecular meshwork cells under various conditions and finds that contractility is context-dependent, shaped by both extracellular and intracellular factors.

The paper constructs a multi-omics single-cell atlas of human RPE and choroid, identifying cell types, aging patterns, and genetic risk factors for AMD.

The paper creates a multi-omics atlas of human trabecular meshwork and ciliary body cells, identifying cell types and regulatory programs linked to glaucoma.

The paper evaluates the computational tool BFEE2 for predicting binding affinities of DVL PDZ domain-peptide complexes in Wnt/{beta}-catenin signaling.