Author

Xuan Bao

University of California, IrvineORCID 0009-0009-4842-2724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioengineering· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Rui CheniD· 4 shared Han CheniD· 2 shared Ismail Yaman· 2 shared J. Timothy Stout· 2 shared Jean LiiD· 2 shared Jianming ShaoiD· 2 shared Jie ZhengiD· 2 shared Jinjing JianiD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersGenomics

Rui ChenORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Genetic & Genomic MedicineGenome MedicinePeer-reviewedOct 31, 2026

Biallelic germline variants in the hematologic malignancy predisposition gene DDX41 cause retinal dystrophy through dysregulation of retinal homeostasis.

Zoéline Mars, Andrea Zanetti, Karolina Kamińska…·Isabelle Perrault

The paper identifies biallelic DDX41 variants in LCA/EOSRD patients and shows they disrupt retinal homeostasis through loss-of-function mechanisms in mouse models.

1 citation

mouseDNA methylation

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GenomicsbioRxivPreprintJul 24, 2026

An Integrated Multi-omics Single Cell Atlas of the Human RPE and Choroid

Jianming Shao, Xuan Bao, Ismail Yaman…·Rui Chen

The paper constructs a multi-omics single-cell atlas of human RPE and choroid, identifying cell types, aging patterns, and genetic risk factors for AMD.

1 citation

humanscRNA-seq

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GenomicsbioRxivPreprintJun 22, 2026

An Integrated muti-omics cell atlas of the human trabecular meshwork and ciliary body

Jinjing Jian, Xuan Bao, Jun Wang…·Rui Chen

The paper creates a multi-omics atlas of human trabecular meshwork and ciliary body cells, identifying cell types and regulatory programs linked to glaucoma.

DOI 10.64898/2026.06.17.732980

humansnRNA-seq

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BioengineeringbioRxivPreprintJan 16, 2026

Monitoring Gene Expression in Retina with Synthetic Serum Markers

Jiaxiong Lu, Sangsin Lee, Meng Wang…·Rui Chen

This study uses synthetic serum markers (RMAs) to monitor retinal gene expression and cell survival through blood tests, showing high sensitivity and non-destructiveness.

DOI 10.64898/2026.01.16.699406

mouseproteomics

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