Author

Jielong Zhou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Yingsheng ZhangiD· 3 shared Mengchen PuiD· 2 shared Weisheng ZhengiD· 2 shared Xiaorong LiiD· 2 shared Bo HuangiD· 1 shared Cheng WangiD· 1 shared Gongxin Peng· 1 shared Hao‐Yu Chang· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioinformatics

Yingsheng ZhangORCID

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Author profile →

3 papers

Recent·Most cited

Sparse Modeling of Genomic Landscape Identifies Pathogenic Processes and Therapeutic Targets in Metastatic Breast Cancer

Mengchen Pu, Kai Tian, Weisheng Zheng, Xiaorong Li, Keyue Fan, Liang Zheng, Jielong Zhou, Yingsheng Zhang

This study uses a deep learning model to identify mutational signatures in metastatic breast cancer and link them to therapeutic targets.

bioRxiv · Aug 29, 2023 · PreprintBioinformatics

Using graph-based model to identify cell specific synthetic lethal effects

Mengchen Pu, Kaiyang Cheng, Xiaorong Li, Yucui Xin, Lanying Wei, Sutong Jin, Weisheng Zheng, Gongxin Peng, Qihong Tang, Jielong Zhou, Yingsheng Zhang

This paper introduces a deep learning model using graph-based representation to predict cell-specific synthetic lethal gene pairs, enhancing cancer precision medicine.

Computational and Structural Biotechnology Journal · Jan 1, 2023Peer-reviewedBioinformatics

Thinking like a structural biologist: A pocket-based 3D molecule generative model fueled by electron density

Lvwei Wang, Rong Bai, Xiaoxuan Shi, Wei Zhang, Yinuo Cui, Xiaoman Wang, Cheng Wang, Hao‐Yu Chang, Yingsheng Zhang, Jielong Zhou, Wei Peng, Wenbiao Zhou, Bo Huang

The paper introduces a 3D molecule generative model using electron density data to create drug-like molecules that match target protein pockets and active compounds.

Scientific Reports · Sep 6, 2022Peer-reviewedBioinformatics