Author

Kai Tian

Peking UniversityORCID 0000-0002-5543-571XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hanhui MaiD· 1 shared Hongye Fu· 1 shared Huang Jie· 1 shared Hui WangiD· 1 shared Jiazhi HuiD· 1 shared Jielong Zhou· 1 shared Keyue Fan· 1 shared Li Yuanjun· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Hanhui MaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 29, 2023

Sparse Modeling of Genomic Landscape Identifies Pathogenic Processes and Therapeutic Targets in Metastatic Breast Cancer

Mengchen Pu, Kai Tian, Weisheng Zheng…·Yingsheng Zhang

This study uses a deep learning model to identify mutational signatures in metastatic breast cancer and link them to therapeutic targets.

DOI 10.1101/2023.08.29.554992

humanwhole-genome sequencing

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 15, 2022

DNA binding domain undergoes dynamic and selective protein-protein interactions to facilitate CTCF insulation

Zhou Rong, Kai Tian, Huang Jie…·Xiong Ji

The paper shows that CTCF's DNA binding domain forms dynamic clusters that interact with insulator proteins and avoid transcriptional activators, revealing a mechanism for its insulation function.

DOI 10.1101/2022.05.15.491938

humanproteomics

𝕏 PostBluesky