The CHIP-LMO7-BAG5 complex controls tau clearance and yields repurposed and newly designed therapeutic candidates for Alzheimer's disease
Ji‐Yoen Kim, Bakhos Tadros, Bhupesh Vaidya, Yan Hong Wei Liang, Sung Yun Jung, Xue Deng, Jin Xu, Huda Yahya Zoghbi
The paper identifies the CHIP-LMO7-BAG5 complex as a regulator of tau clearance and develops therapeutic candidates targeting this complex for Alzheimer's disease.
bioRxiv · Jun 29, 2026 · PreprintNeuroscience