Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures
Huanhuan Li, Minh C. Pham, Jinfeng Teng, Kevin C. O’Connor, Colleen Noviello, Ryan E. Hibbs
The paper presents high-resolution structures of the human muscle AChR and maps epitopes of MG autoantibodies to reveal diverse pathogenic mechanisms.
Cell · May 1, 2025Peer-reviewedNeuroscience