Author

Colleen Noviello

University of California San DiegoORCID 0000-0002-0055-1019Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Ryan E. HibbsiD· 2 shared Biddut Bhattacharjee· 1 shared Huanhuan LiiD· 1 shared J. Michael McIntoshiD· 1 shared Jinfeng Teng· 1 shared Joanna GajewiakiD· 1 shared John P. MayeriD· 1 shared Kevin C. O’ConnoriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Ryan E. HibbsORCID

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2 papers

Recent·Most cited

Shape-Shifting Conotoxins Reveal Divergent Pore-Targeting Mechanisms in Nicotinic Receptors

Biddut Bhattacharjee, Colleen Noviello, Md Mahfuzur Rahman, John P. Mayer, Joanna Gajewiak, J. Michael McIntosh, Ryan E. Hibbs, Michael H. B. Stowell

This study uses cryoEM to reveal how two conotoxins bind differently to nicotinic acetylcholine receptors, showing distinct structural and functional mechanisms despite similar sequences.

Structure · Dec 29, 2025Peer-reviewedNeuroscience

Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures

Huanhuan Li, Minh C. Pham, Jinfeng Teng, Kevin C. O’Connor, Colleen Noviello, Ryan E. Hibbs

The paper presents high-resolution structures of the human muscle AChR and maps epitopes of MG autoantibodies to reveal diverse pathogenic mechanisms.

Cell · May 1, 2025Peer-reviewedNeuroscience