Genetic architecture of immune-mediated thrombotic thrombocytopenic purpura in Han Chinese individuals
Zeyu Gan, Jingjing Jiang, Zilin Lai, Lv Xiong, Yajie Ding, Shanshan Luo, Yu Hu, Xingjie Hao, Jun Deng
This study identifies two genetic loci associated with TTP in Han Chinese individuals, revealing structural variants in HLA-DRB1 that influence autoantigen presentation.
medRxiv · Sep 27, 2026 · PreprintGenetic & Genomic Medicine