Lei Chen

This paper describes a synthetic modular cyanobacterial consortium that enables carbon-negative production of glycerol and derivatives by linking carbon fixation with downstream bioconversion.

This study evolves Synechocystis strains to tolerate high light, finds genetic mutations that improve photosynthesis and biomass, and identifies key genes involved in light tolerance.

This study enhances salt tolerance in Synechocystis sp. PCC 6803 through adaptive evolution, identifying key genes and demonstrating applications for bioremediation of saline environments.

This paper develops a system for inducing A[->]G and C[->]T mutations in E. coli using fusion proteins of DnaG with TadA variants, significantly increasing mutation rates and enabling rapid adaptive evolution.

This study develops genetic toolboxes for Synechococcus sp. PCC 11901 to enhance its use as a carbon-neutral cell factory for producing valuable chemicals from CO2.