Displayed and Encoded Antigens on Adenovirus Vectors Optimize Humoral and Cellular Immune Responses in Rhesus Macaques
Zhenyu Li, Matthew D. J. Dicks, Louisa M. Rose, Rebecca A Russell, Katherine McMahan, Ninaad Lasrado, Joseph P. Nkolola, Erica N. Borducchi, Jinyan Liu, Jayeshbhai Chaudhari, Sumi Biswas, Dan H. Barouch
This study shows that displaying an antigen on adenovirus capsids and encoding it as a transgene enhances both humoral and cellular immune responses in rhesus macaques.
Journal of Virology · Apr 14, 2026Peer-reviewedImmunology