Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation
Guillem Hernández, Maria L. Martins, Nuno P. Fernandes, Tiago Veloso, João Lopes, Tiago Gomes, Tiago N. Cordeiro
This study reveals how the SARS-CoV-2 N-protein's interdomain linker drives dynamic self-assembly and phase separation through coiled-coil interactions.
Nucleic Acids Research · May 28, 2025Peer-reviewedBiophysics