Tiago N. Cordeiro

This study identifies perineurial cells as integrators of leptin and sympathetic outflow, showing their role in obesity protection through barrier function and beta 2 adrenergic receptor regulation.

Ensemblify generates and analyzes conformational ensembles of intrinsically disordered proteins using Monte Carlo sampling and AlphaFold confidence metrics.

The paper shows that C30 self-assembles into complexes stabilized by disulfide bonds, which are required for Tgl-mediated cross-linking during spore coat formation in Bacillus subtilis.

This study shows Fbxo42 promotes degradation of Ataxin-2 granules, enabling Xbp1 translation and triggering cell death during terminal UPR activation.

This study reveals how the SARS-CoV-2 N-protein's interdomain linker drives dynamic self-assembly and phase separation through coiled-coil interactions.

The paper studies the conformational landscapes of full-length Smad2 and Smad4 proteins using an integrative approach and identifies their dynamic structural states and functional implications.

This paper investigates the dimer/monomer propensities of Smad MH1-DNA complexes using structural biology methods, revealing that loop1 sequence determines dimerization and influencing Smad complex composition and DNA motif recognition.