Tiago Gomes

This study identifies perineurial cells as integrators of leptin and sympathetic outflow, showing their role in obesity protection through barrier function and beta 2 adrenergic receptor regulation.

Ensemblify generates and analyzes conformational ensembles of intrinsically disordered proteins using Monte Carlo sampling and AlphaFold confidence metrics.

This study reveals how the SARS-CoV-2 N-protein's interdomain linker drives dynamic self-assembly and phase separation through coiled-coil interactions.

The paper studies the conformational landscapes of full-length Smad2 and Smad4 proteins using an integrative approach and identifies their dynamic structural states and functional implications.

This paper investigates the dimer/monomer propensities of Smad MH1-DNA complexes using structural biology methods, revealing that loop1 sequence determines dimerization and influencing Smad complex composition and DNA motif recognition.