GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling
Rachel K. Lex, Zhicheng Ji, Kristin N. Falkenstein, Weiqiang Zhou, Joanna L Henry, Hongkai Ji, Steven A. Vokes
The paper identifies HH-responsive enhancers that lose acetylation in the absence of Hedgehog signaling and are regulated by GLI repression rather than Polycomb complexes.
eLife · Jan 27, 2020Peer-reviewedDevelopmental Biology