Ex vivo maturation of the malaria parasite egress protease SERA6 aids pathway dissection and inhibitor development.
Chrislaine Martinez, Zahie Taha, Christine R. Collins, Fiona Hackett, Michele S. Y. Tan, Christelle Soudy, Dhira Joshi, Joanna Redmond, Benedict Davies, Sarah Maslen, Mark Skehel, Roger George, Svend Kjær, Michael J. Blackman
This study develops an in vitro system to study SERA6 maturation and validates inhibitors that block malaria parasite egress.
Frontiers in Parasitology · Aug 13, 2026Peer-reviewedBiochemistry