Author

Joanna Stefano

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Benjamin KleavelandiD· 3 shared David P. BarteliD· 3 shared Charlie Y. ShiiD· 2 shared Lara E. ElcavageiD· 2 shared Raghu R. ChivukulaiD· 1 shared Sue‐Jean HongiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

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6 top collaborators · 13 mutual co-author links

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3 shared papersMolecular Biology

Benjamin KleavelandORCID

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3 papers

Recent·Most cited

Derepression of a single microRNA target causes female infertility in mice

Joanna Stefano, Lara E. Elcavage, Sue‐Jean Hong, David P. Bartel, Benjamin Kleaveland

This study shows that derepression of Zeb1, a target of miR-200a/b, causes infertility in mice by disrupting pituitary hormone production and gene expression.

Nucleic Acids Research · Dec 23, 2025Peer-reviewedMolecular Biology

The widespread influence of ZSWIM8 on microRNAs during mouse embryonic development

Charlie Y. Shi, Lara E. Elcavage, Raghu R. Chivukula, Joanna Stefano, Benjamin Kleaveland, David P. Bartel

The paper investigates the role of ZSWIM8 in miRNA degradation during mouse embryonic development, finding that its loss leads to developmental defects and altered miRNA accumulation.

Genome Research · Sep 1, 2023Peer-reviewedMolecular Biology

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

Benjamin Kleaveland, Charlie Y. Shi, Joanna Stefano, David P. Bartel

The lncRNA Cyrano drives multiple-turnover degradation of miR-7 in mouse brain, which protects the circRNA Cdr1as from miR-7-dependent, partly miR-671-sliced destruction.

Cell · Jun 7, 2018Peer-reviewedMolecular Biology✦ In-depth digest