Author

Benjamin Kleaveland

Weill Cornell MedicineORCID 0000-0002-0333-3586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

David P. BarteliD· 3 shared Joanna Stefano· 3 shared Charlie Y. ShiiD· 2 shared Lara E. ElcavageiD· 2 shared Caroline W DunniD· 1 shared Nickolas AlmodovariD· 1 shared Raghu R. ChivukulaiD· 1 shared Sue‐Jean HongiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 14 mutual co-author links

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3 shared papersMolecular Biology

David P. BartelORCID

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4 papers

Recent·Most cited

Argonaute-2 slicing of a domesticated retrotransposon maintains proteostasis and prevents lethal skeletal muscle defects

Nickolas Almodovar, Caroline W Dunn, Benjamin Kleaveland

This study identifies Rtl1 as a key AGO2 slicing substrate in skeletal muscle, showing that AGO2 slicing prevents lethal skeletal muscle defects by repressing a domesticated retrotransposon.

bioRxiv · Aug 21, 2026 · PreprintMolecular Biology

Derepression of a single microRNA target causes female infertility in mice

Joanna Stefano, Lara E. Elcavage, Sue‐Jean Hong, David P. Bartel, Benjamin Kleaveland

This study shows that derepression of Zeb1, a target of miR-200a/b, causes infertility in mice by disrupting pituitary hormone production and gene expression.

Nucleic Acids Research · Dec 23, 2025Peer-reviewedMolecular Biology

The widespread influence of ZSWIM8 on microRNAs during mouse embryonic development

Charlie Y. Shi, Lara E. Elcavage, Raghu R. Chivukula, Joanna Stefano, Benjamin Kleaveland, David P. Bartel

The paper investigates the role of ZSWIM8 in miRNA degradation during mouse embryonic development, finding that its loss leads to developmental defects and altered miRNA accumulation.

Genome Research · Sep 1, 2023Peer-reviewedMolecular Biology

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

Benjamin Kleaveland, Charlie Y. Shi, Joanna Stefano, David P. Bartel

The lncRNA Cyrano drives multiple-turnover degradation of miR-7 in mouse brain, which protects the circRNA Cdr1as from miR-7-dependent, partly miR-671-sliced destruction.

Cell · Jun 7, 2018Peer-reviewedMolecular Biology✦ In-depth digest