Spatiotemporal organisation of residual disease in mouse and human BRCA1-deficient mammary tumours and breast cancer
Demeter Túrós, Morgane Decollogny, Anna Moyseos, Astrid Chanfon, Myriam Siffert, Joanne Bousmar, Lou Romanens, Jean‐Christophe Tille, Olivier Trédan, Sana Intidhar Labidi‐Galy, Alberto Valdeolivas, Sven Rottenberg
This study maps the spatiotemporal organization of minimal residual disease in BRCA1-deficient mouse and human breast tumors, identifying a drug-tolerant EMT-like cell population linked to poor clinical outcomes.
Nature Communications · Jun 11, 2026Peer-reviewedCancer Biology