Author

Myriam Siffert

University of Bern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Sven RottenbergiD· 2 shared Alberto ValdeolivasiD· 1 shared Alexandra A. Duarte· 1 shared Anna Moyseos· 1 shared Astrid Chanfon· 1 shared Demeter TúrósiD· 1 shared Diego DibitettoiD· 1 shared Ewa GogolaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Sven RottenbergORCID

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2 papers

Recent·Most cited

Spatiotemporal organisation of residual disease in mouse and human BRCA1-deficient mammary tumours and breast cancer

Demeter Túrós, Morgane Decollogny, Anna Moyseos, Astrid Chanfon, Myriam Siffert, Joanne Bousmar, Lou Romanens, Jean‐Christophe Tille, Olivier Trédan, Sana Intidhar Labidi‐Galy, Alberto Valdeolivas, Sven Rottenberg

This study maps the spatiotemporal organization of minimal residual disease in BRCA1-deficient mouse and human breast tumors, identifying a drug-tolerant EMT-like cell population linked to poor clinical outcomes.

Nature Communications · Jun 11, 2026Peer-reviewedCancer Biology

MDC1 counteracts restrained replication fork restart and its loss causes chemoresistance in BRCA1/2-deficient mammary tumors

Martin Liptay, Joana S. Barbosa, Ewa Gogola, Alexandra A. Duarte, Diego Dibitetto, Jonas Andreas Schmid, Ismar Klebic, Merve Mutlu, Myriam Siffert, Paola Francica, Israel Salguero, Marieke van de Ven, Renske de Korte‐Grimmerink, Stephen P. Jackson, Jos Jonkers, , Sven Rottenberg

This study identifies MDC1's role in replication fork restart and shows its loss leads to chemoresistance in BRCA1/2-deficient mammary tumors.

bioRxiv · Aug 18, 2022 · PreprintMolecular Biology