Depletion of BRCA1 Potentiates Progestin-Induced Cytoskeletal Changes in an Ovarian Cancer Cell Model
Jocelyn Baquier, Noelle E. Gillis, Caroline H. Diep, Laura J. Mauro, Carol Ann Lange
This study shows that BRCA1 depletion in ovarian cancer cells enhances progestin-induced cytoskeletal changes and migration through altered PR phosphorylation and Rho-GTPase pathways.
bioRxiv · Jan 2, 2026 · PreprintCancer Biology