Potentiating antibiotic treatment using fitness-neutral gene expression perturbations
Peter B. Otoupal, Keesha E. Erickson, Kristen A. Eller, Jocelyn K. Campos, Thomas R. Aunins, Anushree Chatterjee
This paper identifies gene expression perturbations that enhance antibiotic efficacy against MDR bacteria without fitness costs, demonstrating therapeutic potential in both E. coli and Salmonella.
bioRxiv · Aug 15, 2019 · PreprintSynthetic Biology