Author

Joe M Segal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

S Tamir Rashid· 3 shared Samuel J I Blackford· 3 shared Soon Seng Ng· 3 shared Hiromitsu Nakauchi· 2 shared Maria Paola Serra· 2 shared Aileen J F King· 1 shared Alessandra Vigilante· 1 shared Andrew Bonham· 1 shared

Activity by Year

2018-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

S Tamir Rashid

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Author profile →

3 papers

Recent·Most cited

Validation of a library of cGMP-compliant human pluripotent stem cell lines for use in liver therapy

Samuel J I Blackford, Soon Seng Ng, Joe M Segal, Aileen J F King, Jennifer Moore, Michael Sheldon, Dusko Ilic, Anil Dhawan, Ragai Mitry, S Tamir Rashid

The paper validates three cGMP-compliant human pluripotent stem cell lines for their ability to differentiate into functional hepatocytes suitable for liver therapy.

bioRxiv · Apr 10, 2018 · PreprintCell Biology

Conversion of iPS derived hepatic progenitors into scalable, functional and developmentally relevant human organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold engineered from collagen-coated pores of defined size

Soon Seng Ng, Kourosh Saeb-Parsy, Joe M Segal, Maria Paola Serra, Samuel J I Blackford, Marta Horcas Lopez, Da Yoon No, Curtis W Frank, Nam Joon Cho, Hiromitsu Nakauchi, Jeffrey S Glenn, S Tamir Rashid

This paper develops a bioengineered scaffold to generate functional human liver organoids from iPSCs, showing improved morphology, gene expression, and functionality compared to 2D and 3D controls.

bioRxiv · Apr 6, 2018 · PreprintBioengineering

Single-cell analysis identifies EpCAM+/CDH6+/TROP-2- cells as human liver progenitors.

Joe M Segal, Daniel J Wesche, Maria Paola Serra, Bénédicte Oulès, Deniz Kent, Soon Seng Ng, Gozde Kar, Guy Emerton, Samuel J I Blackford, Spyros Darmanis, Rosa Miquel, Tu Vinh, Ryo Yamamoto, Andrew Bonham, Alessandra Vigilante, , S Tamir Rashid

The paper identifies EpCAM+/CDH6+/TROP-2- cells as liver progenitors using single-cell RNA sequencing in human fetal and adult liver tissue.

bioRxiv · Apr 4, 2018 · PreprintCell Biology