Automatic colocalization of high resolution MALDI MSI and Raman imaging applied to cardiac tissue of Fabry disease mouse models
Johann Dierks, Eike Ulrich Brockmann, Paula-Anahi Arias-Loza, Thomas Wilhelm Bocklitz, Peter Nordbeck, Kristina Lorenz, Elen Tolstik, Sven Heiles
The paper develops a multimodal imaging approach combining Raman and AP-MALDI MSI to detect Gb3 accumulation in cardiac tissue of Fabry disease mouse models.
bioRxiv · Nov 27, 2025 · PreprintMolecular Biology