Paula-Anahi Arias-Loza

This study shows TREM2 drives pro-scarring macrophage accumulation in infarcted myocardium, leading to fibrosis and reduced cardiac repair.

This study shows that murine cytomegalovirus infection exacerbates inflammation in Pkp2 mutant mice but not in Ttn mutant mice, highlighting the interaction between genetic predisposition and environmental factors in cardiomyopathy.

The paper develops a multimodal imaging approach combining Raman and AP-MALDI MSI to detect Gb3 accumulation in cardiac tissue of Fabry disease mouse models.

This study shows that IFN-gamma signaling in cardiomyocytes causes metabolic changes in the heart, including increased glucose uptake and reduced oxidative phosphorylation, which resemble changes in aging and heart failure.