SINHCAF/FAM60A links SIN3A function to the hypoxia response and its levels are predictive of cancer patient survival
John Biddlestone, Michael Batie, Alena Shmakova, Daniel Bandarra, Elena V. Knatko, Albena T. Dinkova‐Kostova, Ivan M. Munoz, Ramasubramanian Sundaramoorthy, Tom Owen‐Hughes, Sónia Rocha
This study identifies SINHCAF/FAM60A as a component of the SIN3A-HDAC complex that regulates the hypoxia response and shows its inverse correlation with HIF2 mRNA levels, predicting cancer patient survival.
bioRxiv · Aug 15, 2017 · PreprintMolecular Biology