Etifoxine inhibits NLRP3 inflammasome activity in human and murine myeloid cells
Jordan M. Osmond, John Bradley Williams, Paul McMahan Matthews, David R. Owen, Craig Stephen Moore
This paper shows etifoxine inhibits NLRP3 inflammasome activity in human and murine myeloid cells, with anti-inflammatory effects independent of its known TSPO and GABAA receptor interactions.
bioRxiv · Sep 19, 2023 · PreprintNeuroscience