The role of inflammation in a humanized mouse model of transthyretin cardiac amyloidosis
Xiaokang Wu, Nixuan Cai, John Isaiah Jimenez, Hiroki Kitakata, Gracia Fahed, Alessandro Evangelisti, Alokkumar Jha, Yi-Ping Joseph Woo, Ronglih Liao, Kevin Michael Alexander
This paper develops a humanized mouse model of V122I ATTR-CM and identifies inflammatory pathways involved in its pathogenesis.
bioRxiv · Dec 24, 2024 · PreprintPathology