Effects of Cholesterol Modulation on Cisplatin-Induced Hearing Loss
John Lee, Marcello Peppi, Megan Guidry, Katharine A. Fernandez, Abu Zaffar Chowdhury, Lizhen Wang, Lisa L. Cunningham
This study shows that reducing systemic cholesterol, either through statins or genetic models, protects against cisplatin-induced hearing loss by preserving cochlear outer hair cells.
bioRxiv · Sep 23, 2025 · PreprintNeuroscience