Author

John R. Srouji

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

Anastasia RepouliouiD· 2 shared Cassandra G. M. ExtavouriD· 2 shared Emily L. RivardiD· 2 shared Andrés E. LeschzineriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersEvolutionary Biology

Anastasia RepouliouORCID

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2 papers

Recent·Most cited

Protein sequence evolution underlies interspecies incompatibility of a cell fate determinant

Emily L. Rivard, John R. Srouji, Anastasia Repouliou, Cassandra G. M. Extavour

This study investigates how sequence evolution in the oskar gene leads to functional incompatibility between Drosophila melanogaster and Drosophila virilis, focusing on the OSK domain's role in germ plasm localization.

bioRxiv · Aug 2, 2025 · PreprintEvolutionary Biology

The LOTUS domain of Oskar promotes localisation of both protein and mRNA components of Drosophila germ plasm

Anastasia Repouliou, John R. Srouji, Emily L. Rivard, Andrés E. Leschziner, Cassandra G. M. Extavour

The paper tests Oskar variants in vivo to assess their role in germ plasm assembly, finding that the LOTUS domain is critical for mRNA recruitment despite the current model attributing this function to the OSK domain.

bioRxiv · May 2, 2025 · PreprintDevelopmental Biology