Author

John R. Widger

UNSW Sydney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adam JafféiD· 1 shared Chee Y. Ooi· 1 shared Elvis Pandzic· 1 shared Iveta ŠlapetováiD· 1 shared Jeffry Setiadi· 1 shared Katelin M. AllaniD· 1 shared Laura K. Fawcett· 1 shared Michael J. CarnelliD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Adam JafféORCID

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1 paper

Recent·Most cited

Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect

Sharon L. Wong, Nikhil T. Awatade, Miro A. Astore, Katelin M. Allan, Michael J. Carnell, Iveta Šlapetová, Po‐Chia Chen, Jeffry Setiadi, Elvis Pandzic, Laura K. Fawcett, John R. Widger, Renee M. Whan, Renate Griffith, Chee Y. Ooi, Serdar Kuyucak, , Shafagh A. Waters

The paper characterizes the functional and structural defects of the R352Q CFTR mutation using patient-derived organoids and molecular dynamics simulations, showing residual function restored by potentiators but not correctors.

American Journal of Respiratory Cell and Molecular Biology · Apr 26, 2022Peer-reviewedMolecular Biology