Longitudinal in vivo MR elastography reveals whole-liver viscoelastic involvement in a murine model of hepatocellular carcinoma
Pedro Augusto Dantas de Moraes, Yasmine Safraou, Karolina Krehl, Akvile Häckel, Tobias Haase, Susanne Metzkow, Rafaela V. Silva, Yalei Zang, Jonas Röder, Anja A. Kuehl, Lynn Jeanette Savic, Jürgen Braun, Eyk A. Schellenberger, Ingolf Sack, Jing Guo
This study uses in vivo MR elastography to show early whole-liver viscoelastic changes in a murine HCC model, suggesting biomechanical adaptation beyond the tumor microenvironment.
bioRxiv · Sep 4, 2025 · PreprintBiophysics