Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging
Megan K. Rommelfanger, Marthe Behrends, Yulin Chen, Jonathan Martinez, Martin Bens, Lingyun Xiong, K. Lenhard Rudolph, Adam L. MacLean
This study introduces popInfer, a method for inferring gene regulatory networks from single-cell multiomics data, and applies it to uncover dynamic regulation of hematopoietic stem cell quiescence in mice under different dietary and aging conditions.
bioRxiv · Apr 18, 2023 · PreprintSystems Biology