Author

Megan K. Rommelfanger

University of Southern CaliforniaORCID 0000-0003-3071-7419Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Adam L. MacLeaniD· 3 shared Lingyun XiongiD· 2 shared Andrew P. McMahoniD· 1 shared Fan GaoiD· 1 shared Ingileif B. HallgrímsdóttiriD· 1 shared Jing LiuiD· 1 shared Jinjin GuoiD· 1 shared Jonathan Martinez· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersSystems Biology

Adam L. MacLeanORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMay 6, 2023

Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney

Lingyun Xiong, Jing Liu, Seung Yub Han…·Andrew P. McMahon

The paper identifies androgen receptor-mediated regulation of sexually dimorphic gene expression in the mouse kidney and finds limited conservation in human kidney.

2 citations

mousebulk RNA-seq

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Systems BiologybioRxivPreprintApr 18, 2023

Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging

Megan K. Rommelfanger, Marthe Behrends, Yulin Chen…·Adam L. MacLean

This study introduces popInfer, a method for inferring gene regulatory networks from single-cell multiomics data, and applies it to uncover dynamic regulation of hematopoietic stem cell quiescence in mice under different dietary and aging conditions.

2 citations

mousescRNA-seq

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Systems BiologyDevelopmentPeer-reviewedDec 15, 2021

A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis

Megan K. Rommelfanger, Adam L. MacLean

The paper develops a cell-cell communication model to explain lineage commitment in hematopoiesis by analyzing the GATA1-PU.1 network's role in fate decisions.

17 citations

humanbulk RNA-seq

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