3D MAPs discovers the morphological sequence chondrocytes undergo in the growth plate and the regulatory role of GDF5 in this process
Sarah Rubin, Ankit Agrawal, Johannes Stegmaier, Jonathan Svorai, Yoseph Addadi, Paul Villoutreix, Tomer Stern, Elazar Zelzer
The paper introduces 3D MAPs, a pipeline for analyzing chondrocyte morphology in growth plates, revealing allometric growth strategies and GDF5's regulatory role in tibia development.
bioRxiv · Jul 28, 2020 · PreprintDevelopmental Biology