Ankit Agrawal

This study creates a single-cell atlas of the immunobiliary niche in cholangitis, revealing interactions between type 2 conventional dendritic cells and γδT cells that drive fibrosis.

NiCo identifies extrinsic drivers of cell state modulation by analyzing niche covariation in spatial transcriptomics data.

This study uses single-cell RNA-sequencing and spatial transcriptomics to analyze the spatio-temporal dynamics of the fibrotic niche in cardiac repair after ventricular injury in adult mice, identifying key cell interactions and regulatory mechanisms.

The paper analyzes growth plate architecture in mouse embryos and finds that chondrocyte columns are not formed during embryonic bone elongation, suggesting different cellular mechanisms in pre- and postnatal development.

The paper introduces 3D MAPs, a pipeline for analyzing chondrocyte morphology in growth plates, revealing allometric growth strategies and GDF5's regulatory role in tibia development.

THiCweed detects sequence features in ChIP-seq data by clustering bound regions based on sequence similarity, outperforming existing methods on synthetic and real data.