A behavioral screen for mediators of age-dependent TDP-43 neurodegeneration identifies SF2/SRSF1 among a group of potent suppressors in both neurons and glia.
Jorge Azpurua, Enas A. Elkarim, Marvel Tranquille, Josh Dubnau
The paper identifies SF2/SRSF1 as a suppressor of TDP-43 toxicity in both neurons and glia through a Drosophila behavioral screen.
PLoS Genetics · Nov 1, 2021Peer-reviewedNeuroscience