Phenotyping aldehyde metabolism in humans uncovers novel genetic mutations in aldehyde dehydrogenase 2
Joseph R. White, Freeborn Rwere, Xiaocong Zeng, Leslie S McNeil, Kevin Zhou, Martin S. Angst, Che‐Hong Chen, Daria Mochly‐Rosen, Eric Richard Gross
The paper develops a method to phenotype ALDH2 genetic differences in humans and identifies novel mutations causing inefficient acetaldehyde metabolism after alcohol consumption.
medRxiv · Jun 26, 2020 · PreprintGenetic & Genomic Medicine