The antibiotic phazolicin displays a dual mode of uptake in Gram-negative bacteria
Dmitrii Y. Travin, Armelle Vigouroux, Satomi Inaba‐Inoue, Feng Qu, Romain Jouan, Joy Lachat, Dmitry A. Sutormin, Svetlana A. Dubiley, Konstantinos Beis, S. Moréra, Konstantin Severinov, Peter Mergaert
The paper identifies two distinct transporters, BacA and YejABEF, that mediate the uptake of the peptide antibiotic phazolicin in Sinorhizobium meliloti, reducing resistance acquisition.
bioRxiv · Apr 27, 2022 · PreprintMolecular Biology