Dmitry A. Sutormin

The study links seawater microbiome composition to water-mass origin and transformation in the northeastern Barents Sea and St. Anna Trough, identifying distinct microbial signatures for different water masses.

The paper develops metaSPLiT, a single-cell RNA sequencing method, to reveal sub-species functional specialization in the human gut microbiome.

The paper introduces mapSPLiT, a pooled CRISPRa/i screening platform for bacteria, linking perturbations to single-cell transcriptomes and expanding regulatory networks in E. coli and P. putida.

The paper analyzes microbiomes of three sympatric Arctic sponge species, finding functional convergence and specialization within their symbiotic communities, with shifts linked to temperature changes.

The paper profiles single-cell transcriptomes of Bacteroides fragilis infected with a phage, revealing combinatorial phase-variable expression of defense systems that enable super-resistant cells to avoid phage infection without mutations.

This paper proposes a single moving metal-ion mechanism for DNA-cleavage by type IIA topoisomerases using crystal structures of Staphylococcus aureus DNA gyrase complexes with gepotidacin and zolifodacin.

This study benchmarks DNA isolation methods for marine metagenomics by evaluating eight kits across three sample types, focusing on quality, contamination, and community composition.

The paper shows that TopoI interacts with RNA polymerase in E. coli to prevent R-loop formation by relaxing negative supercoiling during transcription.

The paper identifies two distinct transporters, BacA and YejABEF, that mediate the uptake of the peptide antibiotic phazolicin in Sinorhizobium meliloti, reducing resistance acquisition.