The Genetic Architecture of DNA Replication Timing in Human Pluripotent Stem Cells
Qiliang Ding, Matthew M. Edwards, Ning Wang, Xiang Zhu, Alexa N. Bracci, Michelle L. Hulke, Ya Hu, Yao Tong, Joyce Hsiao, Christine J. Charvet, Sulagna Dia Ghosh, Robert E. Handsaker, Kevin C. Eggan, Florian T. Merkle, Jeannine Gerhardt, , Amnon Koren
This study identifies genetic regulators of DNA replication timing in human pluripotent stem cells, revealing a histone code and combinatorial regulatory mechanisms.
Nature Communications · Nov 19, 2021Peer-reviewedGenomics