HBx enhances CPAP expression via interacting with CREB to promote hepatocarcinogenesis in HBV-associated HCC
Chia-Jui Yen, Shu-Ting Yang, Ruo-Yu Chen, Wenya Huang, Kazuaki Chayama, Ming-Hao Lee, Shiang-Jie Yang, Yu-Wei Hsiao, Ju-Ming Wang, Yih-Jyh Lin, Liang-Yi Hung
This study identifies HBx enhancing CPAP expression through CREB interaction, promoting hepatocarcinogenesis in HBV-associated HCC by increasing NF-κB activation and inflammation.
bioRxiv · Sep 20, 2018 · PreprintCancer Biology