Klotho deficiency promotes skeletal muscle weakness and is associated with impaired motor unit connectivity
Linda A. Bean, Connor Thomas, Juan F. Villa, Alexander J. Fitt, Areli Jannes S. Javier, Akanksha Agrawal, Hanna Whitney, Guilherme Nascimento Dos Santos, Kenneth E. White, Joshua R. Huot, Steven S. Welc
This study shows Klotho deficiency causes skeletal muscle weakness and impaired motor unit connectivity by altering neuromuscular junction structure and function.
International Journal of Molecular Sciences · Aug 19, 2025Peer-reviewedPhysiology